MOXNIC-CL-625 TAB

DOSAGE:

ORAL

OTITIS MEDIA: SINUSITIS; SKIN AND SOFT TISSUE INFECTIONS; UPPER AND LOWER RESPIRATORY TRACT INFECTIONS; SUSEPTILE INFECTIONS: Adult: Based on amoxicillin dose, 250-500 mg every 8 hr or 500-750 mg every 12 hr. Child: Based on amoxicillin dose, 125-250 mg every 8 hr. children weighing <40 hg: 20-40 mg/ kg/day in divided doses every 8 hr. Infants <3 mth: up to 30 mg/kg/day in divided doses every 12hr.

DENTAL ABSCESSES: Adult: Based on amoxicillin dose: 3 g as a single dose, followed by another dose 8 hr later.

ACUTE UNCOMPLICATED URINARY TRACT INFECTIONS: Adult: based on amoxicillin dose: 3g as a single dose, followed by another dose 10-12 hr later.

SEVERE OR RECURRENT RESPIRATORY TRACT INFECTIONS: Adult: Based on amoxicillin dose: 3 g as a single dose with 1g of oral probenecid.

PROPHYLAXIS OF ENDOCARDITIS: Adult: Based on amoxicillin dose: 2 or 3g as a single dose. To be taken 1 hr before the dental procedure.

H. PYLORI INFECTION: Adult: based on amoxicillin dose: 0.75-1 g bid or 500mg tid. To be taken with metronidazole or claithromycin and a PPI or ranitidine bismuth citrate.

Parenteral

SUSCEPTIBLE INFECTIONS: Adult: Based on amoxicillin dose: 500 mg every 8 hr. in severe infections, may increase to 1g every 6 hr. can be given via IM inj or slow IV inj over 3-4 minutes of IV infusion over 30-60 minutes. Child:< 10yr: 50-100 mg/kg/day in divided doses.

CI: Penicillin allergy.

SP: History of allergy especially to cephalosporins, infectious mononucleosis, severe renal impairment.